The Spireites returned from a three-week break to beat Notts County 1-0 at Meadow Lane thanks to a first-half Gavin Gunning free-kick.
James Rowe made three changes from the side that took on Dagenham & Redbridge with Grant Smith coming in for his debut in goal. Joel Taylor and Jak McCourt also returned to the side.
Jack Clarke and new signing Adi Yussuf started on the bench and had a chance of making their debuts for the club.
The home side looked to gain the early advantage as Rueben Rodrigues let fly from the edge of the area; his first-time effort whistled just over the crossbar.
It didn’t take long for the balance of play to start shifting in favour of Chesterfield. Akwasi Asante headed a George Carline cross onto the roof of the net in the 16th minute.
Strike partner Marcus Dinanga was also causing trouble to the opposition defence almost deflecting Luke Pilling’s clearance into the back of the net.
The on-loan striker came close again in the 24th after he got in front of Alex Lacey and his shot from a tight angle was deflected inches wide of the right post.
Eventually the Spireites were rewarded for their continued pressure. Gunning whipped in a free-kick from 30 yards out that evaded a whole bunch of players and nestled into the goal.
The rest of the first half continued in the same way and the Blues went into the break with a one-goal lead.
Notts County started the second half in the same as they did in the first, with a period of sustained pressure. Kyle Wooton nodded an early chance wide of the goal.
Chesterfield looked to break on the counter-attack when Carline did brilliantly to keep the ball in play; Dinanga picked up the loose ball and saw his effort from 20 yards saved by Pilling.
Chances started to come at a premium and Grant Smith was commanding his area well and holding the ball from crosses.
With about ten minutes to go, both Asante and Laurence Maguire broke away and were barreling down on goal, both putting efforts off-target.
Clarke and Yussuf made their debuts coming onto the pitch either side of those chances. Gunning and Asante made way.
Chesterfield continued to defend resiliently and had a chance to wrap it up. Yussuf was played through on goal, but his effort was saved. The final whistle sounded soon after though to signal a massive win in Nottingham.
Chesterfield: G. Smith, Carline, Evans (C), Maguire, Hollis, Taylor, Gunning (Clarke 80), McCourt, Weston, Dinanga (Mandeville 62), Asante (Yussuf 85).
Unused Substitutes: Yarney, M. Smith.